Epigenetics: The Many Faces of Epigenetics in Aging
نویسندگان
چکیده
منابع مشابه
Epigenetics of Aging.
The best-known phenomenon exemplifying epigenetic drift (the alteration of epigenetic patterns during aging) is the gradual decrease of global DNA methylation. Aging cells, different tissue types, as well as a variety of human diseases possess their own distinct DNA methylation profiles, although the functional impact of these is not always clear. DNA methylation appears to be a dynamic tool of...
متن کاملEpigenetics and aging
Aging is the accumulation of changes in an organism over time that leads to reduced viability. Studies in model organisms indicate that aging is genetically determined and that alterations to specific genes can extend or shorten lifespan. Some organisms exhibit negligible aging with no loss of metabolic functions or fertility over time, despite a high metabolic rate, raising the question as to ...
متن کاملEpigenetics and aging.
Over the past two decades, a growing interest on the research of the biological basis of human longevity has emerged, in order to clarify the intricacy of biological and environmental factors affecting (together with stochastic factors) the quality and the rate of human aging. These researches have outlined a complex scenario in which epigenetic marks, such as DNA methylation and numerous histo...
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Today, humans have made incredible leaps in the understanding of genomics, medicine, and genetics. Over the last several decades, our lifespan has increased dramatically thanks to advances in healthcare, sanitation, and drugs. We now are looking for more ways to increase our lifespan, but we have reached a bottleneck in our pursuit for the fountain of youth. Hospitals and powerful medications c...
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ژورنال
عنوان ژورنال: Innovation in Aging
سال: 2020
ISSN: 2399-5300
DOI: 10.1093/geroni/igaa057.2659